Author

Qinyang He

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Dongxin ZhaoiD· 1 shared Guanglei ZhuangiD· 1 shared Huaijiang XiangiD· 1 shared Huiling Mu· 1 shared Jiajia LviD· 1 shared Kaiyan YeiD· 1 shared Li TaniD· 1 shared Libing XiangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Dongxin ZhaoORCID

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1 paper

Recent·Most cited

Targeting CDK12 condensates at nuclear speckles with rationally designed cyclin K molecular glue degraders

Kaiyan Ye, Qinyang He, Yan Cheng, Meiying Zhang, Huiling Mu, Mei‐Chun Cai, Shaoqing Zhou, Huaijiang Xiang, Yuqiao Hou, Yunxia Li, Yinuo Zang, Jiajia Lv, Lin Cheng, Libing Xiang, Dongxin Zhao, , Li Tan

This study identifies CDK12 condensates at nuclear speckles as a therapeutic target and demonstrates that cyclin K molecular glue degraders like HQY1428 disrupt these condensates, inhibiting oncogenic transcription and ovarian cancer growth.

bioRxiv · Mar 31, 2025 · PreprintCancer Biology