Author

Yan Cheng

Chinese Academy of SciencesORCID 0000-0002-0919-672XUnclaimed ORCID profile · follow to get notified of new preprints

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Yan Cheng3 papers · Fudan University

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:plant (other)· 1 Assay:proteomics· 1

Frequent Co-Authors

Chang AniD· 1 shared Chao ShiiD· 1 shared Chongrong KeiD· 1 shared Chunmei Lai· 1 shared Dongxin ZhaoiD· 1 shared Guanglei ZhuangiD· 1 shared Huaijiang XiangiD· 1 shared Huiling Mu· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

Chang AnORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 10, 2026

Metagenomic insights into dose-dependent alterations in the tobacco rhizosphere microbiome by pyrroloquinoline quinone

Liwei Liu, Yanqi Liang, Jiahao Cai…·Chunmei Lai

This study examines how varying concentrations of PQQ affect the tobacco rhizosphere microbiome using metagenomic sequencing, revealing non-monotonic changes in taxonomic and functional profiles.

DOI 10.64898/2026.10.08.757804

plant (other)metagenomics

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Cancer BiologybioRxivPreprintMar 31, 2025

Targeting CDK12 condensates at nuclear speckles with rationally designed cyclin K molecular glue degraders

Kaiyan Ye, Qinyang He, Yan Cheng…·Li Tan

This study identifies CDK12 condensates at nuclear speckles as a therapeutic target and demonstrates that cyclin K molecular glue degraders like HQY1428 disrupt these condensates, inhibiting oncogenic transcription and ovarian cancer growth.

1 citation

humanproteomics

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