Author

Jiajia Lv

Shanghai Jiao Tong UniversityORCID 0000-0002-0016-7981Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Dongxin ZhaoiD· 1 shared Guanglei ZhuangiD· 1 shared Huaijiang XiangiD· 1 shared Huiling Mu· 1 shared Kaiyan YeiD· 1 shared Li TaniD· 1 shared Libing XiangiD· 1 shared Lin ChengiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Dongxin ZhaoORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintMar 31, 2025

Targeting CDK12 condensates at nuclear speckles with rationally designed cyclin K molecular glue degraders

Kaiyan Ye, Qinyang He, Yan Cheng…·Li Tan

This study identifies CDK12 condensates at nuclear speckles as a therapeutic target and demonstrates that cyclin K molecular glue degraders like HQY1428 disrupt these condensates, inhibiting oncogenic transcription and ovarian cancer growth.

1 citation

humanproteomics

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