Author

R. A. Drezek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1 Approach:statistical model· 1

Frequent Co-Authors

P. Bugga· 2 shared V. Asthana· 2 shared A. Asthana· 1 shared A. Ferguson· 1 shared A. Li· 1 shared B. S. Stern· 1 shared D. LeJeune· 1 shared G. Bao· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioengineering

P. Bugga

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Author profile →

3 papers

Recent·Most cited

Expanded Multiplexing on Sensor-Constrained Microfluidic Partitioning Systems

P. K. Kota, H.-A. Vu, D. LeJeune, M. Han, S. Syed, R. G. Baraniuk, R. A. Drezek

This paper introduces an extended MLE method for microfluidic partitioning, enabling broad-range multiplexing in diagnostics using sparse Poisson recovery and ddPCR.

bioRxiv · Dec 23, 2022Bioengineering

Simulation-guided sloppy DNA probe design for mismatch-tolerant hybridization

P. Bugga, V. Asthana, R. A. Drezek

This paper introduces a toehold-based exchange probe that detects nucleic acid sequences with multiple SNPs by incorporating controlled mismatches, showing effectiveness even with up to four mismatches and thermodynamic deviations.

bioRxiv · Dec 20, 2022 · PreprintBioengineering

Development of a Novel Class of Self-Assembling dsRNA Cancer Therapeutics: a Proof of Concept Investigation

V. Asthana, B. S. Stern, Y. Tang, P. Bugga, A. Li, A. Ferguson, A. Asthana, G. Bao, R. A. Drezek

This paper introduces a novel class of self-assembling dsRNA therapeutics that target specific oncogenic sequences and induce apoptosis in cancer cells.

bioRxiv · Apr 22, 2020Bioengineering