Control of ss-glucan exposure by the endo-1,3-glucanase Eng1 in Candida albicans modulates virulence
M. Yang, N. Solis, M. Marshall, R. A. Garleb, T. Zhou, D. Wang, M. Swidergall, E. Pearlman, S. Filler, H. Liu
This study shows that Eng1 and Ywp1 in C. albicans reduce Dectin-1 binding by masking β-glucans, thereby decreasing immune recognition and virulence.
bioRxiv · Sep 7, 2020Microbiology