Author

R. A. Hirst

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

C. O'Callaghan· 2 shared A. A. Straatman-Iwanowska· 1 shared A. Agrotis· 1 shared A. L. David· 1 shared A. Olivo· 1 shared A. Rutman· 1 shared B. C. Jones· 1 shared B. Sina· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

C. O'Callaghan

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Author profile →

2 papers

Recent·Most cited

Single cell-guided prenatal derivation of primary epithelial organoids from the human amniotic and tracheal fluids.

M. F. M. Gerli, G. Cala, M. A. Beesley, B. Sina, L. Tullie, F. Panariello, F. Michielin, K. Y. Sun, J. R. Davidson, F. M. Russo, B. C. Jones, D. Lee, S. Savvidis, T. Xenakis, I. C. Simcock, , P. De Coppi

The paper derives epithelial organoids from human amniotic and tracheal fluids to model congenital malformations and predict disease outcomes.

Nature Medicine · Mar 4, 2024Peer-reviewedCell Biology

High-content screening for rare respiratory diseases: readthrough therapy in primary ciliary dyskinesia

D. D. H. Lee, D. Cardinale, E. Nigro, C. R. Butler, A. Rutman, M. R. Fassad, R. A. Hirst, D. Moulding, A. Agrotis, E. Forsythe, D. Peckham, E. Robson, C. M. Smith, S. Somavarapu, P. L. Beales, , C. O'Callaghan

The paper develops a high-content screening method using differentiated respiratory epithelium from PCD patients to evaluate readthrough therapies for rare respiratory diseases.

bioRxiv · Feb 28, 2020 · PreprintCell Biology