Author

C. R. Butler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. M. Smith· 3 shared C. O'Callaghan· 3 shared R. E. Hynds· 3 shared D. D. H. Lee· 2 shared E. Nigro· 2 shared K.-M. Case· 2 shared P. De Coppi· 2 shared S. M. Janes· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersCell Biology

C. M. Smith

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The emergence of goblet inflammatory or ITGB6hi nasal progenitor cells determines age-associated SARS-CoV-2 pathogenesis

M. Woodall, A.-M. Cujba, K. B. Worlock, K.-M. Case, T. Masonou, M. Yoshida, K. Polanski, N. Huang, R. G. Lindeboom, L. Mamanova, L. Bolt, L. Richardson, S. Ellis, M. Palor, T. Burgoyne, , C. M. Smith

The study identifies age-related differences in nasal epithelial cell responses to SARS-CoV-2 infection, showing distinct progenitor cell dynamics in children and elderly.

bioRxiv · Jan 16, 2023 · PreprintCell Biology

Cell-intrinsic differences between human airway epithelial cells from children and adults

E. F. Maughan, R. E. Hynds, A. Pennycuick, E. Nigro, K. H. C. Gowers, C. Denais, S. Gomez-Lopez, K. A. Lazarus, J. C. Orr, D. R. Pearce, S. E. Clarke, D. D. H. Lee, M. N. J. Woodall, T. Masonou, K.-M. Case, , S. M. Janes

The paper compares airway epithelial cells from children and adults, finding intrinsic differences in transcriptional profiles and regenerative capacity.

bioRxiv · Apr 20, 2020Cell Biology

High-content screening for rare respiratory diseases: readthrough therapy in primary ciliary dyskinesia

D. D. H. Lee, D. Cardinale, E. Nigro, C. R. Butler, A. Rutman, M. R. Fassad, R. A. Hirst, D. Moulding, A. Agrotis, E. Forsythe, D. Peckham, E. Robson, C. M. Smith, S. Somavarapu, P. L. Beales, , C. O'Callaghan

The paper develops a high-content screening method using differentiated respiratory epithelium from PCD patients to evaluate readthrough therapies for rare respiratory diseases.

bioRxiv · Feb 28, 2020 · PreprintCell Biology