Author

R. Ajay Kumar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Madhavan· 2 shared A. Dusthackeer· 1 shared A. K B· 1 shared A. Raj Pushparajan· 1 shared B. M· 1 shared B. Muralikrishnan· 1 shared J. G. Reji· 1 shared L. K. Edison· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

A. Madhavan

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2 papers

Recent·Most cited

Chrysomycin A inhibits the topoisomerase I of Mycobacterium tuberculosis.

B. Muralikrishnan, L. K. Edison, A. Dusthackeer, J. G. Reji, R. Ramachandran, A. Madhavan, R. Ajay Kumar

This study identifies chrysomycin A as an inhibitor of topoisomerase I in Mycobacterium tuberculosis, showing bactericidal activity and synergy with existing anti-TB drugs.

bioRxiv · Jun 23, 2021Biochemistry

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

A. Madhavan, A. K B, A. Raj Pushparajan, B. M, R. Ajay Kumar

The paper shows that ZBTB25 interacts with HDAC1 in MTB-infected macrophages, and inhibiting this interaction promotes autophagy and kills the pathogen.

bioRxiv · Jun 22, 2020Microbiology