BiochemistrybioRxiv
Chrysomycin A inhibits the topoisomerase I of Mycobacterium tuberculosis.
B. Muralikrishnan, L. K. Edison, A. Dusthackeer…·R. Ajay Kumar
This study identifies chrysomycin A as an inhibitor of topoisomerase I in Mycobacterium tuberculosis, showing bactericidal activity and synergy with existing anti-TB drugs.
DOI 10.1038/s41429-022-00503-z