Author

R. Ambrose

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Assay:metagenomics· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:ecology & biodiversity· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Chekaoui· 2 shared D. Newman· 2 shared H. C. J. Ertl· 2 shared M. Hasanpourghadi· 2 shared M. Novikov· 2 shared W. Giles-Davis· 2 shared X. Zhou· 2 shared Z. Xiang· 2 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

A. Chekaoui

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Environmental DNA metabarcoding reveals distinct fish assemblages supported by seagrass (Zostera marina and Zostera pacifica) beds in different geographic settings in Southern California

T. Waters, Z. Gold, A. Obaza, R. Ambrose, R. Eagle

This study uses eDNA metabarcoding to identify fish assemblages in seagrass beds across different geographic settings in Southern California, revealing site-specific biodiversity patterns.

bioRxiv · May 12, 2023 · PreprintEcology

A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation

S. E. Garnish, K. R. Martin, M. Kauppi, V. Jackson, R. Ambrose, V. V. Eng, S. Chiou, Y. Meng, D. Frank, E. C. Tovey Crutchfield, K. M. Patel, A. Jacobsen, G. Atkin-Smith, L. Di Rago, M. Doerflinger, , J. Hildebrand

The paper shows that a common MLKL polymorphism, S132P, enhances necroptotic activity in human cells and impairs recovery from infection in mice.

bioRxiv · Sep 8, 2022 · PreprintImmunology

Prime-boost vaccinations with two serologically distinct chimpanzee adenovirus vectors expressing SARS-CoV-2 spike or nucleocapsid tested in a hamster COVID-19 model

M. Hasanpourghadi, M. Novikov, R. Ambrose, A. Chekaoui, D. Newman, J. Ding, W. Giles-Davis, Z. Xiang, X. Zhou, Q. Liu, K. Swagata, H. C. J. Ertl

The paper tests two chimpanzee adenovirus vectors expressing SARS-CoV-2 spike or nucleocapsid proteins in hamsters, finding that combining them enhances protection against COVID-19.

bioRxiv · Mar 17, 2022 · PreprintImmunology

Pre-clinical testing of two serologically distinct chimpanzee-origin adenovirus vectors expressing spike of SARS-CoV-2

M. Novikov, M. Hasanpourghadi, R. Ambrose, A. Chekaoui, D. Newman, W. Giles-Davis, X. Zhou, Z. Xiang, H. C. J. Ertl

This study tests two distinct chimpanzee adenovirus vectors expressing SARS-CoV-2 spike protein in mice, showing antibody induction and cross-reactivity between variants.

bioRxiv · Feb 23, 2022 · PreprintImmunology