R. CARABEO

Chlamydia trachomatis modulates the expression of JAK-STAT signaling components to attenuate the Type II interferon response of epithelial cells

This study shows Chlamydia trachomatis reduces JAK-STAT pathway components to dampen IFN-gamma signaling in epithelial cells.

Chlamydial YAP activation in host endocervical epithelial cells mediates pro-fibrotic paracrine stimulation of fibroblasts

This paper identifies Chlamydia trachomatis-induced YAP activation in cervical epithelial cells as a driver of fibrosis through paracrine signaling to fibroblasts.

Chlamydia trachomatis induces the transcriptional activity of host YAP in a Hippo-independent fashion

This study shows Chlamydia trachomatis activates host YAP transcriptional activity independently of the Hippo pathway, leading to altered gene expression and potential therapeutic targets.

Host cell amplification of nutritional stress contributes to persistence in Chlamydia trachomatis

This study shows that host cell suppression of GTP biosynthesis amplifies nutritional stress, inducing Chlamydia trachomatis persistence under iron or tryptophan starvation.

The Chlamydia type III effector TarP alters the dynamics and organization of host cell focal adhesions

This study shows that Chlamydia's effector TarP stabilizes focal adhesions by interacting with vinculin, reducing cell motility and enhancing matrix attachment.