Niche-inspired synthetic matrices for epithelial organoid culture
V. Hernandez-Gordillo, T. Kassis, A. Lampejo, G. Choi, M. E. Gamboa, J. S. Gnecco, D. Breault, R. Carrier, L. G. Griffith
This study develops synthetic matrices that support human organoid growth by mimicking the niche environment, showing that local biophysical cues, not bulk properties, drive organoid formation.
bioRxiv · Oct 16, 2019Bioengineering