Author

V. Hernandez-Gordillo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 3 Organism:human· 3 Assay:organoid / primary culture· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

L. G. Griffith· 4 shared J. S. Gnecco· 2 shared T. Kassis· 2 shared A. Lampejo· 1 shared A. T. Brown· 1 shared B. A. Goods· 1 shared B. M. Bhushan· 1 shared C. S. Ives· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersBioengineering

L. G. Griffith

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Author profile →

4 papers

Recent·Most cited

Organoid co-culture model of the cycling human endometrium in a fully-defined syntheticextracellular matrix reveals epithelial-stromal crosstalk

J. S. Gnecco, A. T. Brown, K. Buttrey, C. S. Ives, B. A. Goods, L. Baugh, V. Hernandez-Gordillo, M. Loring, K. Isaacson, L. G. Griffith

This paper develops a synthetic extracellular matrix to model the human endometrium's cyclic changes, revealing epithelial-stromal interactions in health and disease.

bioRxiv · Sep 30, 2021 · PreprintBioengineering

Primary human colonic mucosal barrier crosstalk with super oxygen-sensitive Faecalibacterium prausnitzii in continuous culture

J. Zhang, Y. Huang, J.-Y. Yoon, J. Kemmitt, C. Wright, K. Schneider, P. Sphabmixay, V. Hernandez-Gordillo, S. J. Holcomb, B. M. Bhushan, G. Rohatgi, K. Benton, D. Carpenter, J. Kester, G. Eng, , L. G. Griffith

This study develops a co-culture platform to study interactions between human colonic mucosal barriers and Faecalibacterium prausnitzii, showing anti-inflammatory effects and butyrate's role in modulating TLR3/4.

bioRxiv · Jul 2, 2020Bioengineering

Niche-inspired synthetic matrices for epithelial organoid culture

V. Hernandez-Gordillo, T. Kassis, A. Lampejo, G. Choi, M. E. Gamboa, J. S. Gnecco, D. Breault, R. Carrier, L. G. Griffith

This study develops synthetic matrices that support human organoid growth by mimicking the niche environment, showing that local biophysical cues, not bulk properties, drive organoid formation.

bioRxiv · Oct 16, 2019Bioengineering

OrgaQuant: Intestinal Organoid Localization and Quantification Using Deep Convolutional Neural Networks

T. Kassis, V. Hernandez-Gordillo, R. Langer, L. G. Griffith

OrgaQuant is a deep learning tool that automatically locates and quantifies intestinal organoids in brightfield images using a dataset of manually annotated images.

bioRxiv · Oct 8, 2018Bioengineering