Author

R. E. Heap

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

M. Trost· 3 shared T. Heunis· 2 shared A. Dannoura· 1 shared A. J. Simpson· 1 shared A. Moore· 1 shared A. P. Blain· 1 shared A. Segarra Fas· 1 shared B. Saxty· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

M. Trost

Mutual co-authors in cluster

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3 papers

Recent·Most cited

A MALDI-TOF assay identifies nilotinib as an inhibitor of inflammation in acute myeloid leukaemia

J. L. Marin-Rubio, R. E. Heap, T. Heunis, M. E. Duenas, J. Inns, J. Scott, A. J. Simpson, J. M. Allan, H. Blair, O. Heidenreich, B. Saxty, M. Trost

This study identifies nilotinib as an anti-inflammatory drug using a MALDI-TOF assay in AML-derived monocytes, showing it inhibits the p38-MK2/3 signaling axis.

bioRxiv · Mar 29, 2021 · PreprintCancer Biology

Proteomics characterisation of the L929 cell supernatant and its role in BMDM differentiation

R. E. Heap, J. L. Marin Rubio, J. Peltier, T. Heunis, A. Dannoura, A. Moore, M. Trost

The paper characterizes L929 cell supernatant proteome and shows it induces a stronger anti-inflammatory M1 phenotype in BMDMs compared to M-CSF alone.

bioRxiv · Aug 20, 2020Immunology

Profiling embryonic stem cell differentiation by MALDI TOF mass spectrometry: development of a reproducible and robust sample preparation workflow

R. E. Heap, A. Segarra Fas, A. P. Blain, G. M. Findlay, M. Trost

The paper develops a reproducible MALDI-TOF MS workflow to profile mouse embryonic stem cell differentiation and identifies unique biomarkers.

bioRxiv · Jul 9, 2019Biochemistry