Author

R. E. Jefferson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Chevigne· 1 shared A. Fuglistaler· 1 shared A. Oggier· 1 shared A. Rico Villarreal· 1 shared B. Murat· 1 shared C. Arber· 1 shared F. M. Heidenreich· 1 shared J. S. Paradis· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. Chevigne

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Computational design of dynamic receptor--peptide signaling complexes applied to chemotaxis

R. E. Jefferson, A. Oggier, A. Fuglistaler, N. Camviel, M. Hijazi, A. Rico Villarreal, C. Arber, P. Barth

The paper designs dynamic receptor--peptide signaling complexes for chemotaxis, achieving potent signaling and chemotaxis in human T cells through computational strategies.

bioRxiv · Mar 30, 2022 · PreprintBiophysics

Computationally designed GPCR quaternary structures bias signaling pathway activation

J. S. Paradis, X. Feng, B. Murat, R. E. Jefferson, M. E. Szpakowska, M. Hogue, N. D. Bergkamp, F. M. Heidenreich, M. J. Smit, A. Chevigne, M. Bouvier, P. Barth

The paper designs GPCR quaternary structures to bias signaling pathway activation and identifies a conformational switch controlling G protein vs β-arrestin recruitment.

bioRxiv · Sep 23, 2021Biophysics