Loss of ELK1 has differential effects on age-dependent organ fibrosis and integrin expression
J. T. Cairns, A. Habgood, R. Edwards-Pritchard, C. Wilkinson, I. D. Stewart, J. Leslie, B. C. Blaxall, K. Susztak, S. Alberti, A. Nordheim, F. Oakley, R. G. Jenkins, A. L. Tatler
This study shows that loss of ELK1 leads to age-related fibrosis in the lung and liver but not heart or kidneys, and links reduced ELK1 to cigarette smoke exposure.
bioRxiv · Sep 5, 2019Pathology