Author

J. T. Cairns

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. L. Tatler· 2 shared I. D. Stewart· 2 shared A. E. John· 1 shared A. Habgood· 1 shared A. Nordheim· 1 shared B. C. Blaxall· 1 shared C. E. Brightling· 1 shared C. Wilkinson· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

A. L. Tatler

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2 papers

Recent·Most cited

Lysyl oxidase-like 2 (LOXL2) is Increased in Asthma and Contributes to Asthmatic Airway Remodelling

J. Ramis, R. Middlewick, F. Pappalardo, J. T. Cairns, I. D. Stewart, A. E. John, S.-u. Naveed, R. Krishnan, S. Miller, D. E. Shaw, C. E. Brightling, L. Buttery, F. R. Rose, G. Jenkins, S. R. Johnson, A. L. Tatler

This study shows LOXL2 is increased in asthma and contributes to airway remodelling by enhancing TGFβ activation and ECM stiffness.

bioRxiv · Nov 16, 2020 · PreprintCell Biology

Loss of ELK1 has differential effects on age-dependent organ fibrosis and integrin expression

J. T. Cairns, A. Habgood, R. Edwards-Pritchard, C. Wilkinson, I. D. Stewart, J. Leslie, B. C. Blaxall, K. Susztak, S. Alberti, A. Nordheim, F. Oakley, R. G. Jenkins, A. L. Tatler

This study shows that loss of ELK1 leads to age-related fibrosis in the lung and liver but not heart or kidneys, and links reduced ELK1 to cigarette smoke exposure.

bioRxiv · Sep 5, 2019Pathology