Phage-Antibiotic Synergy Is Driven By A Unique Combination Of Antibacterial Mechanism Of Action And Stoichiometry
C. Gu Liu, S. I. Green, L. Min, J. R. Clark, K. C. Salazar, A. L. Terwilliger, H. Kaplan, B. Trautner, R. F. Ramig, A. W. Maresso
This paper investigates phage-antibiotic synergy by analyzing interactions across antibiotic classes and stoichiometries, finding that synergy depends on antibiotic mechanism, phage burst size, and host environment.
mBio · Aug 25, 2020Peer-reviewedMicrobiology