R. H. Nobrega

TGF-β and BMP subfamily pathways in zebrafish spermatogonial niche: A83-01 and DMH1 inhibitor effects in spermatogonial self-renewal and differentiation

This study investigates the roles of TGF-β and BMP subfamily pathways in zebrafish spermatogonial self-renewal and differentiation using inhibitors A83-01 and DMH1, showing antagonistic effects on spermatogonia fate.

Thyroid hormones deficiency impairs male germ cell development: a cross talk between hypothalamic-pituitary-thyroid, and - gonadal axes in zebrafish

This study shows that thyroid hormone deficiency impairs male germ cell development in zebrafish by disrupting spermatogenesis and testicular function.

Gdnf, a germ cell-derived factor, regulates zebrafish germ cell stemness through the creation of new spermatogonial niches (germ and Sertoli cells) and inhibition of spermatogonial differentiation in an autocrine and paracrine manners

This study shows Gdnf maintains zebrafish germ cell stemness by creating new niches and inhibiting differentiation through autocrine and paracrine mechanisms.

Interaction of thyroid hormones and gonadotropin inhibitory hormone in the multifactorial control of zebrafish (Danio rerio) spermatogenesis

This study investigates how thyroid hormones and gonadotropin inhibitory hormone interact to regulate zebrafish spermatogenesis, showing thyroid hormones modulate Gnih's inhibitory effects on gonadotropin-induced spermatogenesis.

CAN CARBON NANOFIBERS AFFECT ANUROFAUNA? STUDY INVOLVING NEOTROPICAL Physalaemus cuvieri (Fitzinger, 1826) TADPOLES

This study investigates the toxic effects of carbon nanofibers on Physalaemus cuvieri tadpoles, finding oxidative stress, neurotoxicity, and metabolic disruption.

Zebrafish studies on the vaccine candidate to COVID-19, the Spike protein: Production of antibody and adverse reaction

This study uses zebrafish to test a COVID-19 vaccine candidate, showing antibody production and adverse reactions similar to human severe cases.