Author

R. Heslop

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:scRNA-seq· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2

Frequent Co-Authors

A. MacLeod· 2 shared P. Chandrasegaran· 2 shared A. Brito Lira· 1 shared A. Cooper· 1 shared A. N. Lestari· 1 shared B. Cheaib· 1 shared C. Bentley-Abbot· 1 shared C. Loney· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. MacLeod

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Spatially-resolved single cell transcriptomics reveal a critical role for γδ T cells in the control of skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection

J. F. Q. Alcala, M. C. Sinton, P. Chandrasegaran, A. N. Lestari, R. Heslop, B. Cheaib, J. Ogunsola, D. M. Ngoyi, N. R. K. Swar, A. Cooper, S. B. Coffelt, A. MacLeod

This study uses spatial and single-cell transcriptomics to show that γδ T cells and adipocytes collaborate to control skin inflammation and adipose tissue wasting during chronic Trypanosoma brucei infection.

bioRxiv · Mar 1, 2023 · PreprintImmunology

Genome-wide libraries for protozoan pathogens drug target screening using yeast surface display

R. Heslop, M. Gao, A. Brito Lira, T. Sternlieb, M. Loock, S. R. Sanghi, I. Cestari

The paper develops a method to construct genome-wide libraries for yeast surface display and identifies drug targets in protozoan pathogens using a fitness screen.

bioRxiv · Nov 17, 2022Microbiology

Integrative single cell and spatial transcriptomic analysis reveal reciprocal microglia - plasma cell crosstalk in the mouse brain during chronic Trypanosoma brucei infection

J. F. Quintana Alcala, P. Chandrasegaran, M. Sinton, E. M. Briggs, T. D. Otto, R. Heslop, C. Bentley-Abbot, C. Loney, L. de Lecea, N. A. Mabbott, A. MacLeod

This study uses single cell and spatial transcriptomics to identify microglia-plasma cell interactions in the mouse brain during chronic T. brucei infection.

bioRxiv · Mar 25, 2022 · PreprintPathology