Author

D. M. Ngoyi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 3 Organism:mouse· 3 Assay:scRNA-seq· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Approach:experimental assay· 1

Frequent Co-Authors

A. MacLeod· 2 shared J. Ogunsola· 2 shared M. C. Sinton· 2 shared P. Chandrasegaran· 2 shared A. Cooper· 1 shared A. N. Lestari· 1 shared A. Sayeed· 1 shared B. Cheaib· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersImmunology

A. MacLeod

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Author profile →

3 papers

Recent·Most cited

The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection

J. F. Quintana Alcala, M. C. Sinton, P. Chandrasegaran, L. K. Dubey, J. Ogunsola, M. A. Samman, M. Haley, G. McConnell, N. R. Kuispond Swar, D. M. Ngoyi, D. Bending, L. de Lecea, A. MacLeod, N. A. Mabbott

This study shows that chronic Trypanosoma brucei infection in mice causes meningeal lymphoid aggregates with autoreactive B cells and autoantibodies against brain antigens.

bioRxiv · Apr 30, 2023 · PreprintImmunology

Spatially-resolved single cell transcriptomics reveal a critical role for γδ T cells in the control of skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection

J. F. Q. Alcala, M. C. Sinton, P. Chandrasegaran, A. N. Lestari, R. Heslop, B. Cheaib, J. Ogunsola, D. M. Ngoyi, N. R. K. Swar, A. Cooper, S. B. Coffelt, A. MacLeod

This study uses spatial and single-cell transcriptomics to show that γδ T cells and adipocytes collaborate to control skin inflammation and adipose tissue wasting during chronic Trypanosoma brucei infection.

bioRxiv · Mar 1, 2023 · PreprintImmunology

VSGs expressed during natural T. b. gambiense infection exhibit extensive sequence divergence and a subspecies-specific expression bias

J. So, S. Sudlow, A. Sayeed, T. Grudda, S. Deborggraeve, D. M. Ngoyi, D. K. Desamber, B. Wickstead, V. Lejon, M. R. Mugnier

This study identifies VSG expression patterns in T. b. gambiense infections, revealing subspecies-specific biases and sequence divergence.

bioRxiv · Sep 9, 2021Microbiology