Author

R. I. Seinstra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

E. A. A. Nollen· 2 shared A. E. X. Brown· 1 shared C. G. Riedel· 1 shared E. M. Jorgensen· 1 shared G. E. Janssens· 1 shared J. E. X. Richmond· 1 shared L. Gungordu· 1 shared L. Janssen· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

E. A. A. Nollen

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2 papers

Recent·Most cited

Rebalancing the motor circuit restores movement in a Caenorhabditis elegans model for TDP-43-toxicity

M. Koopman, L. Gungordu, L. Janssen, R. I. Seinstra, J. E. X. Richmond, N. Okerlund, R. Wardenaar, P. Islam, A. E. X. Brown, E. M. Jorgensen, E. A. A. Nollen

This study identifies that rebalancing excitatory and inhibitory inputs in C. elegans restores movement in a TDP-43 toxicity model by synergizing neurotransmitter system enhancements.

bioRxiv · Oct 24, 2023 · PreprintCell Biology

Transcriptomics-based screening identifies pharmacological inhibition of Hsp90 as a means to defer aging

G. E. Janssens, X.-X. Lin, L. Millan-Arino, R. I. Seinstra, N. Stroustrup, E. A. A. Nollen, C. G. Riedel

The paper uses transcriptomics to screen for aging-deferring compounds, identifying Hsp90 inhibitors as potential geroprotectors.

bioRxiv · Nov 14, 2018Cell Biology