BiochemistrybioRxiv
A cautionary note on the use of N-acetylcysteine as a reactive oxygen species antagonist to assess copper mediated cell death.
R. E. Graham, R. J. R. Elliott, A. F. Munro, N. O. Carragher
This paper shows that N-acetylcysteine reduces copper uptake rather than quenching reactive oxygen species, challenging the current understanding of copper-induced cell death mechanisms.
DOI 10.1371/journal.pone.0294297