Author

R. J. Rawle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:imaging· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

P. M. Kasson· 2 shared A. Lam· 1 shared A. M. Villamil Giraldo· 1 shared A. Pabis· 1 shared A. Park· 1 shared B. A. Lee· 1 shared D. Vujovic· 1 shared K. D. Azarm· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

P. M. Kasson

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4 papers

Recent·Most cited

Single virus assay reveals membrane determinants and mechanistic features of Sendai virus binding

A. Lam, O. O. Kirkland, P. F. Anderson, N. Seetharaman, D. Vujovic, P. A. Thibault, K. D. Azarm, B. A. Lee, R. J. Rawle

This study uses a single virus assay to investigate Sendai virus binding mechanisms, identifying receptor structural features, cooperative binding, cholesterol dependence, and a rolling mobility mechanism.

bioRxiv · Nov 23, 2021Biophysics

Kinetic Modeling of West Nile Virus Fusion Indicates an Off-pathway State

A. Park, R. J. Rawle

The paper revises a previous simulation of WNV fusion and finds an off-pathway state is necessary, suggesting flaviviruses may share this mechanism.

ACS Infectious Diseases · Dec 11, 2020Peer-reviewedBiophysics

Influenza hemagglutinin drives viral entry via two sequential intramembrane mechanisms

A. Pabis, R. J. Rawle, P. M. Kasson

The paper uses molecular dynamics simulations to show influenza hemagglutinin drives fusion via two sequential intramembrane mechanisms: lipid tail protrusion/stalk formation and distal leaflet engagement/curvature.

bioRxiv · Jan 30, 2020Biophysics

Detecting and controlling dye effects in single-virus fusion experiments

R. J. Rawle, A. M. Villamil Giraldo, S. G. Boxer, P. M. Kasson

The paper shows fluorescent dyes can alter viral membrane fusion efficiency and kinetics, and provides a method to minimize these effects.

bioRxiv · May 23, 2019Biophysics