S. G. Boxer

Membrane localization accelerates association under conditions relevant to cellular signaling

The paper compares association rates of a signaling reaction in solution and on membranes, finding membrane localization significantly increases rates in larger cells.

The Interplay of Electrostatics and Chemical Positioning in the Evolution of Antibiotic Resistance in TEM β-Lactamases

The paper analyzes the evolutionary trajectory of TEM β-lactamases to understand how electrostatics and chemical positioning contribute to antibiotic resistance and catalytic function.

Single-virus content mixing assay reveals cholesterol-enhanced influenza membrane fusion efficiency

This paper introduces a single-virus content mixing assay to study influenza membrane fusion efficiency, showing that target membrane cholesterol increases content mixing efficiency and reduces content loss.

Target membrane cholesterol modulates single influenza virus membrane fusion efficiency but not rate

This study develops a receptor-free assay to show that target membrane cholesterol increases IAV fusion efficiency but not rate, independent of receptor binding.

Detecting and controlling dye effects in single-virus fusion experiments

The paper shows fluorescent dyes can alter viral membrane fusion efficiency and kinetics, and provides a method to minimize these effects.