A novel multi SNP based method for the identification of subspecies and associated lineages and sub-lineages of the Mycobacterium tuberculosis complex by whole genome sequencing
S. I. W. Lipworth, R. Jajou, H. de Neeling, P. Bradley, W. van der Hoek, G. Maphalala, M. Bonnet, E. Sanchez-Padilla, R. Diel, S. Niemann, Z. Iqbal, G. Smith, T. Peto, D. Crook, T. M. Walker, D. van Soolingen
This paper introduces SNP-IT, a method using whole genome sequencing to identify subspecies and lineages of Mycobacterium tuberculosis complex, revealing high prevalence of M. orygis in UK clinical isolates.
bioRxiv · Jan 5, 2018Microbiology