ImmunologyFASEB BioAdvancesPeer-reviewed
Human inborn errors of long-chain fatty acid oxidation show impaired inflammatory responses to TLR4-ligand LPS
S. Mosegaard, K. Twayana, S. Denis…·C. K. Holm
This study shows that mutations in ETFDH and ACADVL, which are involved in long-chain fatty acid oxidation, impair inflammatory responses to LPS by reducing TLR4 expression and cytokine production.
DOI 10.1096/fba.2024-00060