Ancestral Roles of the Fam20C Family of Secreted Protein Kinases Revealed by Functional Analysis in C. elegans
A. Gerson-Gurwitz, C. A. Worby, K.-Y. Lee, R. Khaliullin, J. Bouffard, D. Cheerambathur, E. J. Cram, K. Oegema, J. E. Dixon, A. Desai
This study identifies FAMK-1, the C. elegans ortholog of Fam20C, as essential for fertility, embryogenesis, and development through its role in maintaining cellular partitions and responding to mechanical strain.
bioRxiv · Jul 6, 2018Cell Biology