Integrating genotypes and phenotypes improves long-term forecasts of seasonal influenza A/H3N2 evolution
J. Huddleston, J. R. Barnes, T. Rowe, R. Kondor, D. E. Wentworth, L. Whittaker, B. Ermetal, R. S. Daniels, J. W. McCauley, S. Fujisaki, K. Nakamura, N. Kishida, S. Watanabe, H. Hasegawa, I. Barr, , T. Bedford
This study develops a forecasting framework for influenza A/H3N2 evolution by integrating phenotypic antigenic drift data with sequence-based fitness estimates, showing improved long-term predictions.
bioRxiv · Jun 12, 2020Evolutionary Biology