Author

J. R. Barnes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 6 Organism:human· 3 Organism:mouse· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1

Frequent Co-Authors

D. E. Wentworth· 5 shared D. Cui· 4 shared J. Hossain· 4 shared L. Wang· 4 shared N. Jiang· 4 shared B. Zhou· 3 shared M. Currier· 3 shared M. Wilson· 3 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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5 shared papersMicrobiology

D. E. Wentworth

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Genetic drift and purifying selection shape within-host influenza A virus populations during natural swine infections

D. VanInsberghe, D. S. McBride, J. DaSilva, T. J. Stark, M. S. Y. Lau, S. S. Shepard, J. R. Barnes, A. Bowman, A. C. Lowen, K. Koelle

This study examines within-host influenza A virus diversity and evolution in swine, finding low genetic diversity and evidence of purifying selection and genetic drift.

bioRxiv · Oct 23, 2023Evolutionary Biology

Bivalent mRNA vaccine improves antibody-mediated neutralization of many SARS-CoV-2 Omicron lineage variants

N. Jiang, L. Wang, M. Hatta, C. Feng, M. Currier, X. Lin, J. Hossain, D. Cui, B. R. Mann, N. A. Kovacs, W. Wang, G. Atteberry, M. Wilson, R. Chau, K. A. Lacek, , B. Zhou

This study evaluates the neutralizing antibody response to bivalent mRNA vaccines against multiple Omicron variants, showing enhanced neutralization against BQ.1 and BQ.1.1.

bioRxiv · Jan 8, 2023 · PreprintMicrobiology

Differential neutralization and inhibition of SARS-CoV-2 variants by antibodies elicited by COVID-19 mRNA vaccines

L. Wang, M. H. Kainulainen, N. Jiang, H. Di, G. Bonenfant, L. Mills, M. Currier, P. Shrivastava-Ranjan, B. M. Calderon, M. Sheth, B. R. Mann, J. Hossain, X. Lin, S. Lester, E. Pusch, , Davis

This study evaluates how well antibodies from mRNA vaccines neutralize SARS-CoV-2 variants, finding that Omicron shows the most escape but booster doses maintain moderate neutralizing activity.

bioRxiv · Nov 24, 2021Microbiology

Avian influenza A viruses reassort and diversify differently in mallards and mammals

K. Ganti, A. Bagga, J. DaSilva, S. S. Shepard, J. R. Barnes, S. A. Shriner, K. Koelle, A. C. Lowen

This study compares avian influenza A virus reassortment in mallards and guinea pigs, finding higher reassortant frequencies and diversity in mallards.

bioRxiv · Feb 8, 2021Microbiology

SARS-CoV-2 susceptibility of cell lines and substrates commonly used in diagnosis and isolation of influenza and other viruses

L. Wang, X. Fan, G. Bonenfant, D. Cui, J. Hossain, N. Jiang, G. Larson, M. Currier, J. Liddell, M. Wilson, A. Tamin, J. Harcourt, J. Ciomperlik-Patton, H. Pang, N. Dybdahl-Sissoko, , B. Zhou

This study evaluates SARS-CoV-2 susceptibility in cell lines used for influenza and other virus diagnosis, finding that some are permissive while others are not, with MDCK cells being insusceptible due to low ACE2 expression.

bioRxiv · Jan 4, 2021Microbiology

SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility

B. Zhou, T. T. N. Thao, D. Hoffmann, A. Taddeo, N. Ebert, F. Labroussaa, A. Pohlmann, J. King, J. Portmann, N. J. Halwe, L. Ulrich, B. S. Trueb, J. N. Kelly, X. Fan, B. Hoffmann, , M. Beer

This study shows the SARS-CoV-2 D614G variant has enhanced replication and transmissibility in animal models, explaining its global dominance.

bioRxiv · Oct 27, 2020Microbiology

Integrating genotypes and phenotypes improves long-term forecasts of seasonal influenza A/H3N2 evolution

J. Huddleston, J. R. Barnes, T. Rowe, R. Kondor, D. E. Wentworth, L. Whittaker, B. Ermetal, R. S. Daniels, J. W. McCauley, S. Fujisaki, K. Nakamura, N. Kishida, S. Watanabe, H. Hasegawa, I. Barr, , T. Bedford

This study develops a forecasting framework for influenza A/H3N2 evolution by integrating phenotypic antigenic drift data with sequence-based fitness estimates, showing improved long-term predictions.

bioRxiv · Jun 12, 2020Evolutionary Biology

Mitigating Pandemic Risk with Influenza A Virus Field Surveillance at a Swine-Human Interface

B. L. Rambo-Martin, M. W. Keller, M. M. Wilson, J. M. Nolting, T. K. Anderson, A. L. Vincent, U. Bagal, Y. Jang, E. B. Neuhaus, C. T. Davis, A. S. Bowman, D. E. Wentworth, J. R. Barnes

The paper describes using field-derived nanopore sequencing to identify a novel swine influenza A virus that posed a pandemic risk, leading to the development of a vaccine candidate and real-time public health response.

bioRxiv · Mar 21, 2019 · PreprintMicrobiology