A microRNA expression signature in infant t(4;11) MLL-AF4+ BCP-ALL uncovers novel therapeutic targets
C. Malouf, A. Duguid, G. Camiolo, L. Nitsche, H. Jakobczyk, R. Kotecha, R. Anderson, N. Barrett, O. Smith, K. Ottersbach
This study identifies three microRNAs downregulated in MLL-AF4+ BCP-ALL and shows that targeting their downstream genes with existing drugs reduces leukemia burden.
bioRxiv · Jan 12, 2023 · PreprintCancer Biology