Author

C. Malouf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Duguid· 1 shared A. P. Gomes· 1 shared A. Pacis· 1 shared A. Robert· 1 shared C. L. Kleinman· 1 shared G. Camiolo· 1 shared G. Macleod· 1 shared H. Jakobczyk· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Duguid

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Targeting the dependence on PIK3C3-mTORC1 signaling in dormancy-prone breast cancer cells blunts metastasis initiation

I. E. Elkholi, A. Robert, C. Malouf, H. Kuasne, S. Drapela, G. Macleod, S. Hebert, A. Pacis, V. Calderon, C. L. Kleinman, A. P. Gomes, J. A. Aguirre-Ghiso, M. Park, S. Angers, J.-F. Cote

This study identifies Pik3c3 as a vulnerability in dormancy-prone breast cancer cells, showing its inhibition reduces metastasis in preclinical models.

bioRxiv · Aug 2, 2023Cancer Biology

A microRNA expression signature in infant t(4;11) MLL-AF4+ BCP-ALL uncovers novel therapeutic targets

C. Malouf, A. Duguid, G. Camiolo, L. Nitsche, H. Jakobczyk, R. Kotecha, R. Anderson, N. Barrett, O. Smith, K. Ottersbach

This study identifies three microRNAs downregulated in MLL-AF4+ BCP-ALL and shows that targeting their downstream genes with existing drugs reduces leukemia burden.

bioRxiv · Jan 12, 2023 · PreprintCancer Biology