Author

N. Barrett

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Duguid· 1 shared A. Maxfield· 1 shared C. Malouf· 1 shared D. Dwyer· 1 shared D. Gakpo· 1 shared D. Williams· 1 shared F. Borriello· 1 shared F. Pucci· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. Duguid

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A microRNA expression signature in infant t(4;11) MLL-AF4+ BCP-ALL uncovers novel therapeutic targets

C. Malouf, A. Duguid, G. Camiolo, L. Nitsche, H. Jakobczyk, R. Kotecha, R. Anderson, N. Barrett, O. Smith, K. Ottersbach

This study identifies three microRNAs downregulated in MLL-AF4+ BCP-ALL and shows that targeting their downstream genes with existing drugs reduces leukemia burden.

bioRxiv · Jan 12, 2023 · PreprintCancer Biology

Type 2 Inflammation Drives an Airway Basal Stem Cell Program Through Insulin Receptor Substrate Signaling

X. Wang, N. Hallen, M. Lee, S. Samuchiwal, Q. Ye, K. Buchheit, A. Maxfield, R. Roditi, R. Bergmark, N. Bhattacharyya, T. Ryan, D. Gakpo, S. Raychaudhuri, D. Dwyer, T. M. Laidlaw, , N. Barrett

This study identifies BCAM as a marker of airway basal stem cells and shows that T2 cytokines drive their expansion via IRS signaling in CRSwNP.

bioRxiv · Oct 13, 2022Immunology

The physical form of microbial ligands bypasses the need for dendritic cell migration to stimulate adaptive immunity

F. Borriello, R. Spreafico, V. Poli, J. Chou, N. Barrett, L. Lacanfora, M. Franco, L. Marongiu, Y. Iwakura, F. Pucci, M. Kruppa, Z. Ma, D. Williams, I. Zanoni

This study shows that soluble fungal polysaccharides are immunosilent in peripheral tissues but become potent immunogens in draining lymph nodes without requiring dendritic cell migration.

bioRxiv · Mar 3, 2020 · PreprintImmunology