Non-hierarchical, RhlR-regulated acyl-homoserine lactone quorum sensing in a cystic fibrosis isolate of Pseudomonas aeruginosa
R. L. Cruz, K. L. Asfahl, S. Van den Bossche, T. Coenye, A. Crabbe, A. A. Dandekar
The paper shows that a LasR-null Pseudomonas aeruginosa isolate uses RhlR for quorum sensing and virulence, suggesting RhlR as a therapeutic target in chronic infections.
bioRxiv · Sep 2, 2019Microbiology