Author

R. L. Duncan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

N. S. Trompeter· 2 shared A. N. A. Aryee· 1 shared C. J. Farino· 1 shared C. R. Cooper· 1 shared J. D. Gardinier· 1 shared J. H. Slater· 1 shared J. P. Gleghorn· 1 shared L. Hurd· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

N. S. Trompeter

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Extracellular Matrix Stiffness Alters TRPV4 Regulation in Chondrocytes

N. S. Trompeter, C. J. Farino, M. Griffin, R. Skinner, O. A. Banda, J. P. Gleghorn, J. H. Slater, R. L. Duncan

This study shows that softer cartilage substrates reduce TRPV4-mediated calcium influx and increase chondrocyte apoptosis, which can be mitigated by TRPV4 agonism.

bioRxiv · Sep 14, 2021 · PreprintCell Biology

In Vitro Assessment of Efficacy and Cytotoxicity of Prunus africana Extracts on Prostate Cancer C4-2 Cells

P. C. Asuzu, A. N. A. Aryee, N. Trompeter, Y. Mann, S. A. Besong, R. L. Duncan, C. R. Cooper

This study evaluates the cytotoxic effects of Prunus africana extracts on prostate cancer C4-2 cells, finding that bark and root extracts inhibit cell growth more effectively than leaf extracts.

bioRxiv · Mar 14, 2021 · PreprintCancer Biology

Insulin-like Growth Factor-1 Regulates the Mechanosensitivity of Chondrocytes by Modulating TRPV4

N. S. Trompeter, J. D. Gardinier, V. M. DeBarros, M. Boggs, V. Gangadharan, W. J. Cain, L. Hurd, R. L. Duncan

This study shows IGF-1 modulates TRPV4 channel activity in chondrocytes by increasing cell stiffness, reducing hypotonic-induced calcium flux and ATP release.

bioRxiv · Mar 10, 2020Cell Biology