Author

R. L. Guest

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

B. K. Hammer· 1 shared E. A. Court· 1 shared J. L. Waldon· 1 shared K. A. MacGillivray· 1 shared K. A. Schock· 1 shared S. L. Ng· 1 shared S. Wiesenfeld· 1 shared T. J. Silhavy· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperEvolutionary Biology

B. K. Hammer

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2 papers

Recent·Most cited

Trade-offs constrain adaptive pathways to T6 survival

K. A. MacGillivray, S. L. Ng, S. Wiesenfeld, R. L. Guest, T. Jubery, T. J. Silhavy, W. C. Ratcliff, B. K. Hammer

This study uses experimental evolution to show that Escherichia coli evolves resistance to Vibrio cholerae's Type VI Secretion System (T6) through specific mutations, but these mutations come with fitness costs.

bioRxiv · Sep 2, 2022Evolutionary Biology

Impaired Efflux of the Siderophore Enterobactin Induces Envelope Stress in Escherichia coli

R. L. Guest, E. A. Court, J. L. Waldon, K. A. Schock, T. L. Raivio

This study shows that impaired efflux of enterobactin in E. coli activates the Cpx response, leading to envelope stress and down-regulation of enterobactin biosynthesis.

Frontiers in Microbiology · Dec 6, 2019Peer-reviewedMicrobiology