T. L. Raivio

NlpE is an OmpA-associated outer membrane sensor of the Cpx envelope stress response

This study identifies NlpE as an OmpA-associated sensor that activates the Cpx envelope stress response in surface-adhered Gram-negative bacteria by transducing signals from OmpA overexpression.

Simulated colonic fluid replicates the in vivo growth capabilities of Citrobacter rodentium cpxRA mutants and uncovers additive effects of Cpx regulated genes on fitness

This study shows that C. rodentium cpxRA mutants have reduced colonization and virulence in mice, mirroring their growth defects in simulated colonic fluid, suggesting that multiple Cpx-regulated genes collectively impact fitness.

Simulated colonic fluid replicates the in vivo growth capabilities of Citrobacter rodentium mutants and highlights a critical role for the Cpx envelope stress response in mediating stressors encountered in the gastrointestinal tract

The paper shows that Cpx envelope stress response mutants of Citrobacter rodentium have growth defects in simulated colonic fluid and reduced virulence in mice.

Isolation and characterization of a novel temperate Escherichia coli bacteriophage, Kapi1, which modifies the O-antigen and contributes to the competitiveness of its host during colonization of the murine gastrointestinal tract.

Isolation and characterization of a novel bacteriophage, Kapi1, capable of O-antigen modification in commensal Escherichia coli.

This study isolates and characterizes a novel temperate bacteriophage, Kapi1, which modifies the O-antigen of its commensal Escherichia coli host.

Impaired Efflux of the Siderophore Enterobactin Induces Envelope Stress in Escherichia coli

This study shows that impaired efflux of enterobactin in E. coli activates the Cpx response, leading to envelope stress and down-regulation of enterobactin biosynthesis.