Author

R. L. Unckless

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 7 Microbiology· 1

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Organism:Drosophila· 5 Approach:statistical model· 4 Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:yeast· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

S. E. Zanders· 2 shared A. Atadurdyyeva· 1 shared A. G. Clark· 1 shared A. Krishnapura· 1 shared B. Y. Rubinstein· 1 shared C.-H. Chang· 1 shared D. Bachtrog· 1 shared E. M. Knoles· 1 shared

Activity by Year

2017-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersEvolutionary Biology

S. E. Zanders

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Author profile →

8 papers

Recent·Most cited

Meiotic drive, postzygotic isolation, and the Snowball Effect

R. L. Unckless

The paper shows that hybrid sterility caused by meiotic drive can lead to postzygotic isolation genes increasing linearly with substitutions, contradicting the snowball effect prediction.

bioRxiv · Nov 14, 2023 · PreprintEvolutionary Biology

Diversification and recurrent adaptation of the synaptonemal complex in Drosophila

R. Zakerzade, C.-H. Chang, K. Chatla, A. Krishnapura, S. P. Appiah, J. Zhang, R. L. Unckless, J. Blumenstiel, D. Bachtrog, K. H. Wei

This study examines the evolutionary dynamics of the synaptonemal complex in Drosophila, revealing recurrent positive selection and diversification of SC genes through duplications and regulatory changes.

bioRxiv · Oct 20, 2023 · PreprintEvolutionary Biology

Wolbachia enhances the survival of Drosophila infected with fungal pathogens

J. I. Perlmutter, A. Atadurdyyeva, M. E. Schedl, R. L. Unckless

This study shows Wolbachia increases Drosophila survival and fertility when infected with fungal pathogens, suggesting broader pathogen-blocking capabilities beyond viruses.

bioRxiv · Sep 30, 2023 · PreprintMicrobiology

Modeling the Evolution of Populations with Multiple Killer Meiotic Drivers

J. F. L. Hernandez, B. Y. Rubinstein, R. L. Unckless, S. E. Zanders

The paper models the evolution of two meiotic drivers in a population, showing how duplication and divergence can lead to fixation and impact synthetic gene drive design.

bioRxiv · Sep 28, 2023 · PreprintEvolutionary Biology

Hoisted with his own petard: how sex-ratio meiotic drive in Drosophila affinis creates resistance alleles that limit its spread

W.-J. Ma, E. M. Knoles, K. B. Patch, M. M. Shoaib, R. L. Unckless

The paper shows meiotic drive in Drosophila affinis increases Y chromosome nondisjunction, creating resistance alleles that limit the spread of the sex-ratio X chromosome.

bioRxiv · Feb 14, 2022Evolutionary Biology

Atypical meiosis can be adaptive in outcrossed S. pombe due to wtf meiotic drivers

M. A. Bravo Nunez, I. M. Sabbarini, L. E. Eide, R. L. Unckless, S. E. Zanders

The paper shows that wtf meiotic drivers in S. pombe can create a fitness landscape where atypical gametes are advantageous, reducing the cost of meiotic fidelity mutations and potentially increasing their benefit.

bioRxiv · Apr 28, 2020Evolutionary Biology

Balancing selection drives maintenance of geneticvariation in Drosophila antimicrobial peptides

J. R. Chapman, T. Hill, R. L. Unckless

This study shows balancing selection maintains genetic variation in Drosophila antimicrobial peptides across species, with evidence in both D. melanogaster and D. mauritiana.

bioRxiv · Apr 11, 2018Evolutionary Biology

Evolutionary dynamics of male reproductive genes in the Drosophila virilis subgroup

Y. H. Ahmed-Braimah, R. L. Unckless, A. G. Clark

The paper examines the evolutionary dynamics of male reproductive genes in Drosophila virilis subgroup species, identifying SFPs under strong selection and linked to reproductive incompatibilities.

bioRxiv · Feb 25, 2017Evolutionary Biology