Author

R. LeGraw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:organoid / primary culture· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

J. Hislop· 2 shared M. R. Ebrahimkhani· 2 shared S. Kiani· 2 shared A. Hill· 1 shared A. J. Davidson· 1 shared A. Przepiorski· 1 shared A. Silva-Barbosa· 1 shared A. Watson· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

J. Hislop

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Author profile →

2 papers

Recent·Most cited

Genetically engineering endothelial niche in human kidney organoids enables multilineage maturation, vascularization, and de novo cell types

J. C. Maggiore, R. LeGraw, A. Przepiorski, J. Velazquez, C. Chaney, E. Streeter, A. Silva-Barbosa, J. Franks, J. Hislop, A. Hill, H. Wu, K. Pfister, S. E. Howden, S. C. Watkins, M. Little, , N. A. Hukriede

This paper genetically engineers an endothelial niche in human kidney organoids to enhance vascularization, maturation, and the emergence of new cell types.

bioRxiv · May 30, 2023Bioengineering

Synthetic Maturation of Multilineage Human Liver Organoids via Genetically Guided Engineering

J. J. Velazquez, R. LeGraw, F. Moghadam, Y. Tan, J. Kilbourne, J. Hislop, S. Liu, D. Cats, S. M. Chuva de Sousa Lopes, C. Plaisier, P. Cahan, S. Kiani, M. R. Ebrahimkhani

This paper demonstrates genetic engineering of liver organoids to enhance maturation and functionality through CRISPR and transcription factor overexpression.

bioRxiv · May 10, 2020Bioengineering