Author

R. M. Cronin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

K. R. Nicholson· 3 shared P. A. Champion· 3 shared A. R. Menon· 2 shared D. M. Tobin· 2 shared M. Champion· 2 shared M. K. Jennisch· 2 shared B. S. Jones· 1 shared D. D. Hu· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

K. R. Nicholson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The antagonistic transcription factors, EspM and EspN, regulate the ESX-1 secretion system in M. marinum

K. R. Nicholson, R. M. Cronin, R. J. Prest, A. R. Menon, Y. Yang, M. K. Jennisch, M. Champion, D. M. Tobin, P. A. Champion

This study identifies EspN as a critical transcription factor regulating the ESX-1 system in M. marinum, which is essential for macrophage infection and disease burden, but its activity is masked by EspM under laboratory conditions.

bioRxiv · Jan 9, 2024Microbiology

The loss of the PDIM/PGL virulence lipids causes differential secretion of ESX-1 substrates in Mycobacterium marinum

B. S. Jones, D. D. Hu, K. R. Nicholson, R. M. Cronin, M. Champion, P. A. Champion

This study shows that loss of PDIM and PGL lipids in M. marinum reduces specific ESX-1 substrate secretion, impacting pathogenesis.

bioRxiv · Jan 9, 2024 · PreprintMicrobiology

The EspN transcription factor is an infection-dependent regulator of the ESX-1 system in M. marinum

K. R. Nicholson, R. M. Cronin, A. R. Menon, M. K. Jennisch, D. M. Tobin, P. A. Champion

This study identifies EspN as an infection-dependent transcription factor that regulates ESX-1 gene expression during mycobacterial infection, but not under standard lab conditions.

bioRxiv · Feb 15, 2023 · PreprintMicrobiology