R. N. Gutenkunst

The paper shows that shifts in mutation bias can increase the probability of beneficial mutations, promoting the emergence of mutator strains.

This paper develops diffusion models for polyploid demographic history and applies them to infer subgenome exchange rates in allotetraploid shepherds purse.

The paper simulates domestication processes to analyze fitness effect distributions and shows challenges in inferring beneficial selection and demographic history from site frequency spectra.

The paper develops a method to infer genome-wide correlations of mutation fitness effects between populations and finds that these correlations are inversely related to genetic differentiation.

This study uses demogenomic modeling to show early European farmers arose from post-LGM mixing of Near Eastern and Western hunter-gatherer populations and experienced extreme genetic drift during westward expansion.

dadi.CUDA accelerates population genetic inference on GPUs, enabling complex models with minimal user effort.

This paper introduces HyDe-CNN, a convolutional neural network method for inferring hybridization scenarios using genomic data, and applies it to Heliconius butterflies.

The paper introduces stdpopsim, a community-maintained library for population genetic models, to standardize simulations and facilitate benchmarking of inference tools.

This study develops a method to infer demographic history from SNP frequency data in inbred species, showing it accurately estimates demography and inbreeding even in highly inbred populations.