Author

R. Nusse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

M. Fish· 3 shared A. Sarkar· 2 shared M. Morri· 2 shared N. Neff· 2 shared P. Wu· 2 shared T. Anbarchian· 2 shared Y. Jin· 2 shared A. M. Martinez Jaimes· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

M. Fish

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cholangiocytic differentiation drives cell proliferation in hepatoblastoma through Wnt-dependent FGF19 signaling

P. V. Wu, M. Fish, F. K. Hazard, C. Zhu, S. Vennam, H. E. Walton, M. Morri, N. Neff, R. B. West, R. Nusse

The paper identifies FGF19 as a paracrine signal driving tumor growth in hepatoblastoma through Wnt-dependent mechanisms and biliary lineage activation.

bioRxiv · Jun 8, 2023Cancer Biology

Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver.

A. Sarkar, Y. Jin, B. C. DeFelice, C. Y. Logan, Y. Yang, T. Anbarchian, P. Wu, M. Morri, N. Neff, H. Nguyen, E. Rulifson, M. Fish, A. M. Martinez Jaimes, R. Nusse

This study shows intermittent fasting induces rapid hepatocyte proliferation in mice to maintain liver-to-body-mass ratio, challenging the view that liver tissue is quiescent unless injured.

bioRxiv · Oct 16, 2021Cell Biology

Hepatocyte Cell Cycle Progression Depends on a Transcriptional Repressor Cascade Downstream of Wnt Signaling

Y. Jin, T. Anbarchian, P. Wu, A. Sarkar, M. Fish, R. Nusse

The paper identifies a transcriptional repressor cascade downstream of Wnt signaling that controls hepatocyte cell cycle progression by repressing E2F7 and E2F8.

bioRxiv · Oct 15, 2021 · PreprintCell Biology

β-catenin-Mediated Wnt Signal Transduction Proceeds Through an Endocytosis-Independent Mechanism

E. Y. Rim, L. K. Kinney, R. Nusse

This study investigates whether endocytosis is required for Wnt signal transduction by disrupting endocytic pathways in mouse embryonic stem cells and finding no effect on β-catenin nuclear translocation or target gene transcription.

bioRxiv · Feb 13, 2020Cell Biology