Author

R. S. McGee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:variant effect prediction· 1 Organism:yeast· 1

Frequent Co-Authors

B. Kerr· 2 shared O. Kosterlitz· 2 shared A. Kaznatcheev· 1 shared B. Werner· 1 shared C. T. Bergstrom· 1 shared D. Petrov· 1 shared E. M. Top· 1 shared G. Kinsler· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersEvolutionary Biology

B. Kerr

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Author profile →

3 papers

Recent·Most cited

Improving the accuracy of bulk fitness assays by correcting barcode processing biases

R. S. McGee, G. Kinsler, D. Petrov, M. Tikhonov

The paper develops a computational method to correct barcode processing biases in bulk fitness assays, improving fitness estimates in yeast variant libraries.

bioRxiv · Oct 31, 2023Evolutionary Biology

Evolutionary crowdsourcing: alignment of fitness landscapes allows cross-species adaptation of a horizontally transferred gene

O. Kosterlitz, N. Grassi, B. Werner, R. S. McGee, E. M. Top, B. Kerr

The paper examines how horizontal gene transfer affects gene evolution across species by aligning fitness landscapes and shows that adaptive evolution in one species can translate to another.

bioRxiv · Sep 13, 2022Evolutionary Biology

The cost of information acquisition by natural selection

R. S. McGee, O. Kosterlitz, A. Kaznatcheev, B. Kerr, C. T. Bergstrom

This paper challenges Kimura's theory on the cost of information acquisition by natural selection using experimental evolution of E. coli and computational learning theory.

bioRxiv · Jul 2, 2022 · PreprintEvolutionary Biology