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R. S. Underwood

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Immunology· 1

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Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

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C. B. Chhan· 1 shared E. R. Troemel· 1 shared E. Tecle· 1 shared L. Franklin· 1 shared W. Hanna-Rose· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperImmunology

C. B. Chhan

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ImmunologybioRxivFeb 3, 2021

The purine nucleoside phosphorylase pnp-1 regulates epithelial cell resistance to infection in C. elegans

E. Tecle, C. B. Chhan, L. Franklin…·E. R. Troemel

This paper identifies pnp-1 as a negative regulator of immune responses in C. elegans, showing that its loss increases resistance to both intracellular and extracellular pathogens.

DOI 10.1371/journal.ppat.1009350

C. elegansbulk RNA-seq

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