Author

E. R. Troemel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 6 Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Assay:imaging· 1

Frequent Co-Authors

V. Lazetic· 3 shared K. C. Reddy· 2 shared S. S. Gang· 2 shared Y.-T. Chang· 2 shared A. G. Fraser· 1 shared A. W. Reinke· 1 shared C. B. Chhan· 1 shared C. Mok· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersImmunology

V. Lazetic

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Multiple pals gene modules control a balance between immunity and development in Caenorhabditis elegans

V. Lazetic, M. J. Blanchard, T. Bui, E. R. Troemel

This study identifies multiple pals genes that regulate the balance between immunity and development in C. elegans by acting as ON/OFF switches for the Intracellular Pathogen Response.

bioRxiv · Jan 15, 2023Immunology

A pals-25 gain-of-function allele triggers systemic resistance against natural pathogens of C. elegans

S. S. Gang, M. Grover, K. C. Reddy, D. Raman, Y.-T. Chang, D. C. Ekiert, M. Barkoulas, E. R. Troemel

This paper identifies a PALS-25 gain-of-function mutant in C. elegans that activates immune responses against both epidermal and intestinal pathogens through cross-tissue signaling.

bioRxiv · Jun 28, 2022Immunology

RNA fluorescence in situ hybridization (FISH) to visualize microbial colonization and infection in the Caenorhabditis elegans intestines

D. Rivera, V. Lazetic, E. R. Troemel, R. J. Luallen

This paper introduces RNA FISH as a method to detect, quantify, and identify microbes in C. elegans intestines, including bacteria and pathogens like microsporidia and viruses.

bioRxiv · Feb 26, 2022 · PreprintMicrobiology

The predicted bZIP transcription factor ZIP-1 promotes resistance to intracellular infection in Caenorhabditis elegans

V. Lazetic, F. Wu, L. B. Cohen, K. C. Reddy, Y.-T. Chang, S. S. Gang, G. Bhabha, E. R. Troemel

This study identifies ZIP-1, a bZIP transcription factor, as a central regulator of the Intracellular Pathogen Response in C. elegans, enhancing resistance to viral and fungal infections.

Nature Communications · Jan 10, 2022Peer-reviewedImmunology

An intestinally secreted host factor promotes microsporidia invasion of C. elegans

H. T. El Jarkass, C. Mok, M. R. Schertzberg, A. G. Fraser, E. R. Troemel, A. W. Reinke

This study identifies a secreted host protein, AAIM-1, that promotes microsporidia invasion of C. elegans and reveals trade-offs in host defense against different pathogens.

bioRxiv · Jul 12, 2021Microbiology

The purine nucleoside phosphorylase pnp-1 regulates epithelial cell resistance to infection in C. elegans

E. Tecle, C. B. Chhan, L. Franklin, R. S. Underwood, W. Hanna-Rose, E. R. Troemel

This paper identifies pnp-1 as a negative regulator of immune responses in C. elegans, showing that its loss increases resistance to both intracellular and extracellular pathogens.

bioRxiv · Feb 3, 2021Immunology