R. Sanjuan

Viral entry is a weak barrier to zoonosis

The paper experimentally tests the ability of viral receptor-binding proteins from 100+ enveloped RNA viruses to enter human cells, finding that most can do so, with variation among families and host factors playing a role.

Targeted phage hunting to specific Klebsiella pneumoniae clinical isolates is an efficient antibiotic resistance and infection control strategy

The paper isolates and characterizes phages targeting Klebsiella pneumoniae clinical isolates, showing that specific phage hunting is more effective than broad-spectrum approaches for infection control.

Temperature impacts SARS-CoV-2 spike fusogenicity and evolution

This study shows that temperature affects SARS-CoV-2 spike fusogenicity and evolution, with higher temperatures increasing fusion and specific mutations showing temperature-dependent effects.

Cell type-specific adaptation of the SARS-CoV-2 spike

This study shows how SARS-CoV-2 spike protein adapts to different human cell types through mutations that affect entry efficiency and receptor affinity.

An efficient plasmid-based system for the recovery of recombinant vesicular stomatitis virus encoding foreign glycoproteins

This paper describes an efficient plasmid-based system for producing recombinant VSV encoding foreign glycoproteins, validated with glycoproteins from multiple viral families.

Resistance of Omicron subvariants BA.2.75.2, BA.4.6 and BQ.1.1 to neutralizing antibodies

This study evaluates the neutralizing antibody resistance of SARS-CoV-2 Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to monoclonal antibodies and sera from vaccinated individuals.

Enveloped viruses show increased propensity to cross-species transmission and zoonosis

The paper analyzes 12,000 mammalian virus-host associations to show enveloped viruses are more likely to cross-species transmit and cause zoonosis than non-enveloped viruses.

Genetic determinants of host tropism in Klebsiella phages

The paper identifies genetic factors determining host tropism in Klebsiella phages by testing phage-host interactions and analyzing capsule diversity and depolymerase sequences.

The evolution of collective infectious units in viruses

This study models the evolutionary advantages and disadvantages of collective infectious units in viruses, finding they are favored when multiple genomes enhance cell productivity and packaging efficiency.