R. Schneiter

Perilipin 3 promotes the formation of membrane domains enriched in diacylglycerol and lipid droplet biogenesis proteins

Necator americanus Ancylostoma secreted protein-2 (Na-ASP-2) selectively binds an ascaroside (ascr#3)

This study investigates whether Na-ASP-2 binds to ascarosides or their fatty acid moieties, finding that ascaroside fatty acids specifically bind to Na-ASP-2's palmitic acid binding cavity.

The surface of lipid droplets constitutes a barrier for endoplasmic reticulum residential integral membrane spanning proteins

The paper investigates whether ER-resident integral membrane proteins can localize to lipid droplet surfaces and finds that they are excluded due to the LD surface acting as a barrier.

Seipin and Nem1 establish discrete ER subdomains to initiate yeast lipid droplet biogenesis

The paper identifies Seipin (Fld1) and Nem1 as proteins that define discrete ER subdomains necessary for recruiting TAG synthases and other factors to initiate yeast lipid droplet biogenesis.

Lipid droplet biogenesis is driven by a liquid-liquid phase separation.

The paper shows that lipid droplet formation results from liquid-liquid phase separation, influenced by ER membrane properties and lipid composition.