Author

V. Zoni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Approach:statistical model· 3 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1

Frequent Co-Authors

S. Vanni· 5 shared P. Campomanes· 3 shared A. R. Thiam· 2 shared A. Bacle· 1 shared A. Colom· 1 shared A. Kovalenko· 1 shared A. Roux· 1 shared D. Nicastro· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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5 shared papersCell Biology

S. Vanni

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Author profile →

5 papers

Recent·Most cited

Triglyceride lipolysis driven by glucose restriction triggers liquid-crystalline phase transitions and proteome remodeling of lipid droplets

S. Rogers, L. Gui, A. Kovalenko, V. Zoni, M. Carpentier, K. Ramji, K. Ben Mbarek, A. Bacle, P. Fuchs, P. Campomanes, E. Reetz, N. O. Speer, E. Reynolds, A. R. Thiam, S. Vanni, , W. M. Henne

The paper shows glucose restriction induces liquid-crystalline phase transitions in lipid droplets by promoting TG lipolysis, which alters lipid composition and remodels the proteome.

bioRxiv · Apr 15, 2022Cell Biology

Re-charging your fats: Charmm36 parameters for neutral lipids triacylglycerol and diacylglycerol

P. Campomanes, J. Prabhu, V. Zoni, S. Vanni

The paper develops new CHARMM36 parameters for triacylglycerols and diacylglycerols to better reproduce their interfacial properties and behavior in lipid assemblies.

bioRxiv · Sep 29, 2021Biophysics

Seipin accumulates and traps diacylglycerols and triglycerides in its ring-like structure

V. Zoni, W. Shinoda, S. Vanni

This study uses molecular dynamics simulations to show that seipin clusters triglycerides and diacylglycerol in its ring-like structure, promoting lipid droplet formation by remodeling ER membranes.

bioRxiv · Oct 27, 2020Cell Biology

Lipid droplet biogenesis is driven by a liquid-liquid phase separation.

V. Zoni, R. Khaddaj, P. Campomanes, A. R. Thiam, R. Schneiter, S. Vanni

The paper shows that lipid droplet formation results from liquid-liquid phase separation, influenced by ER membrane properties and lipid composition.

bioRxiv · Jan 23, 2020Cell Biology

Conserved function of ether lipids and sphingolipids in the early secretory pathway

N. Jimenez, M. Leonetti, V. Zoni, A. Colom, S. Feng, N. R. Iyengar, S. Matile, A. Roux, S. Vanni, J. S. Weissman, H. Riezman

The paper identifies hypersensitive mutants in lipid biosynthesis and trafficking genes in sphingolipid-depleted cells and shows coordinate regulation of ether and sphingolipids.

bioRxiv · Dec 19, 2019Biochemistry