R. Silva-Rocha

Identification and functional analysis of novel stress-resistance genes from metagenomes of extreme environments

The paper identifies and functionally characterizes novel stress-resistance genes from extreme environment metagenomes and demonstrates their ability to enhance bacterial tolerance to multiple stress conditions.

Metagenomic insights for antimicrobial resistance surveillance in soils with different land uses in Brazil

This study examines how different land uses in Brazil affect soil microbial communities and antimicrobial resistance gene dynamics.

Nanopore sequencing provides rapid and reliable insight into microbial profiles of Intensive Care Units

This study evaluates nanopore sequencing's reliability for microbial profiling in ICU samples compared to Illumina, showing it can provide useful community insights despite lower throughput in complex samples.

Combining functional and structural genomics to track antibiotic resistance genes in mobile elements in clinical bacterial strains

This study identifies antibiotic resistance genes and plasmids in clinical bacterial strains from Brazil, revealing shared resistance mechanisms and novel plasmids that could spread multidrug resistance.

Functional characterization of clinical isolates of the opportunistic fungal pathogen Aspergillus nidulans

This study characterizes two clinical isolates of A. nidulans, showing differences in growth, metabolism, stress response, and virulence compared to a reference strain.

Microbial communities profiling in intensive care units expose limitations in current sanitary standards

This study profiles microbial communities in ICU and NICU surfaces, revealing distinct microbiota and highlighting limitations in current cleaning practices for reducing HAI-related bacteria.

CRZ1 regulator and calcium cooperatively modulate holocellulases gene expression in Trichoderma reesei QM6a

This study investigates the role of CRZ1 and calcium signaling in regulating holocellulases gene expression in T. reesei QM6a, showing their synergistic and independent effects on gene regulation.

Assessing and characterising the repertoire of constitutive promoter elements in soil metagenomic libraries in Escherichia coli

The paper develops a framework to assess promoter elements in soil metagenomic libraries using fluorescence assays and computational methods, finding ~1% of promoters are accessible in Escherichia coli.

Systematic identification of novel regulatory interactions controlling biofilm formation in the bacterium Escherichia coli

The paper identifies 8 new regulatory interactions controlling biofilm formation in E. coli using computational analysis, reporter assays, and physiological experiments.