Author

R. Simeone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

A. Cappelletto· 1 shared C. Astarie-Dequeker· 1 shared C. Chalut· 1 shared C. Guilhot· 1 shared E. Haanappel· 1 shared E. Schneider· 1 shared F. Sayes· 1 shared H. Ali· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPathology

A. Cappelletto

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2 papers

Recent·Most cited

SARS-CoV-2 Spike protein activates TMEM16F-mediated platelet pro-coagulant activity

A. Cappelletto, H. E. Allan, M. Crescente, E. Schneider, R. Bussani, H. Ali, I. Secco, S. Vodret, R. Simeone, L. Mascaretti, S. Zacchigna, T. D. Warner, M. Giacca

This paper shows that SARS-CoV-2 Spike protein activates TMEM16F in platelets, enhancing pro-coagulant activity and thrombosis, which is inhibited by Niclosamide and Clofazimine.

bioRxiv · Dec 14, 2021 · PreprintPathology

Phthiocerol dimycocerosates from Mycobacterium tuberculosis increase the membrane activity of bacterial effectors and host receptors

J. Augenstreich, E. Haanappel, F. Sayes, R. Simeone, V. Guillet, S. Mazeres, C. Chalut, L. Mourey, R. Brosch, C. Guilhot, C. Astarie-Dequeker

This study shows that phthiocerol dimycocerosates (DIM) from Mycobacterium tuberculosis increase membrane activity of both bacterial effectors and host receptors, aiding immune evasion.

bioRxiv · May 13, 2020Microbiology